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Antibacterial effects of elastomeric ligatures coated with bacterial nanocellulose

Antibacterial effects of elastomeric ligatures coated with Kombucha-synthesized bacterial nanocellulose against streptococcus mutans Randomized Clinical

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181121041713N5
Enrollment
72
Registered
2023-10-22
Start date
2023-10-28
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antibacterial effects of elastomeric ligatures coated with Kombucha-synthesized bacterial nanocellulose against streptococcus mutans.

Interventions

Intervention 1: Intervention group: A minimum of ?? brackets will be used for patients. fixed pre adjusted edgewise appliances (Mini Master Bracket, ?.???-in MBT prescription
American Orthodontics, USA) with a slot size of ?.???x?.??? inch will be used in all patients. The same type of composite and adhesive will be used for bracket bonding in all patients. After primary l

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 30 Years

Inclusion criteria

Inclusion criteria: Male and female patients Age 15 to 30 years non pregnant No significant medical history or drug use No anti-inflammatory or antibiotic medications taken within ? months prior to the study No chewing gum or mouthwash use in the week before and during the study habit of brushing twice daily with fluoride toothpaste No history of periodontal therapy or current periodontal disease Probing depth less than ? mm across the entire dentition No gingivitis or active carious lesion Gingival index and plaque index (Silness-Löe) value <1

Exclusion criteria

Exclusion criteria: Diseases and medication use likely to affect dental biofilm Pregnancy Poor oral hygiene Active periodontal disease Severe crowding of anterior teeth or malposition of the lateral incisor likely to interfere with the cleaning of the tooth surface Smoking History of mouth breathing

Design outcomes

Primary

MeasureTime frame
Bacterial colony counting. Timepoint: The beginning of the study and days 7, 14, 21 and 28. Method of measurement: Counting the number of bacterial colonies after sampling.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Neda Babanouri

Shiraz University of Medical Sciences

babanouri@sums.ac.ir+98 71 3626 3193

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026