Skip to content

Effect of Berberine mouthwash on pain caused by orthodontic treatments

Effect of Berberine mouthwash on pain caused by elastomeric Seprator placement

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181115041667N1
Enrollment
60
Registered
2019-06-08
Start date
2019-06-04
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The pain caused by the separator placement. Chronic intractable pain

Interventions

Intervention 1: Intervention group: They must use the Berberine mouthwash(prepared in the Ahvaz Jundishapur University Of Medical Sciences) for 3 days, threewice a day, each time 10 CC for 1 minutes.

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: The samples are in the age range of 18-35, who can execute the study carefully and sign the consent form voluntarily The samples lack any specific systemic disease (such as gastrointestinal and coagulation diseases, etc.) The selected teeth are vital and have no endodontic problems The selected teeth have no periodontic problems The sample doesn't mention any pain in other teeth or other parts of the oral cavity The contact of the first permanent molar with its adjacent teeth is tight so that the banding of the first permanent molar in the beginning of the treatment requires two-way separating ( is checked using dental floss) Lack of space in the desired jaw There is a tooth in front of first permanent molar in front jaw

Exclusion criteria

Exclusion criteria: Taking any medication during the study Separator loss Not completing the questionnaire Improper use of mouthwash History of allergy to Berberine Pregnancy or breastfeeding

Design outcomes

Primary

MeasureTime frame
Pain scale based on Visual Analogue Scale. Timepoint: Immediately after separator placement, 2 hours later and 6 hours later on the first day, at 10 am and 6 am on the second and third days, at 10 am on the seventh day. Method of measurement: Description of the patient's pain based on the Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Seyede Zeynab Eftekhari

Ahvaz University of Medical Sciences

eftekhari-z@ajums.ac.ir+98 61 3320 5319

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026