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The effect of injection of dextrose solution on the severity of knee pain

Dextrose prolotherapy effects on the Pain of Knee Osteoarthritis: Comparison of Injection in Acupuncture Points versus Non-Acupuncture points

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181114041657N1
Enrollment
26
Registered
2018-12-08
Start date
2019-04-04
Completion date
Unknown
Last updated
2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: In the first intervention group, 8 ml of dextrose 20% and 2 ml of lidocaine 1% were injected three times at intervals of one week at acupuncture points. Interventio

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with knee osteoarthritis Over 50 years of age Less than 30 minutes of morning stiffness Crepitus on active motion Bony tenderness Bony enlargement No palpable warmth of synovium

Exclusion criteria

Exclusion criteria: Injection of steroid drugs in the last 2 months Diabetes Candidate for knee surgery Previous treatment with dextrose injection Knee Infections in the last three months Knee inflammation Daily opioid Use History of arthritis Arthritis after infection Joint dysplasia Congenital anomaly Crystalopathy Arthritis after injury Malignancy Vascular necrosis bmi>30

Design outcomes

Primary

MeasureTime frame
Knee pain severity. Timepoint: Before the intervention, one month and two month after the last injection. Method of measurement: Using the Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC).;Morning Stiffness. Timepoint: Before the intervention, one month and two month after the last injection. Method of measurement: Using the Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC).;Physical activity. Timepoint: Before the intervention, one month and two month after the last injection. Method of measurement: Using the Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArash Barghi

Sanandaj University of Medical Sciences

drarash1979@gmail.com+98 87 3366 4653

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026