Gastroesophageal reflux. Oesophageal reflux NOS
Conditions
Interventions
Intervention 1: Intervention group: Injection of 8 million stem cells derived from human adipose tissue injection, suspended in 3 ml buffer phosphate solution, by endoscopy in the lower esophageal sph
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age of 18 to 60 years Without hiatal herniation Without barretts esophagus Without chronic disease Without pregnancy Without morbidly obese Gastroesophageal reflux Proven weakness of the lower esophageal sphincter
Exclusion criteria
Exclusion criteria: Those who are very old and it is difficult to get data from them Individuals with chronic illnesses, such as heart or kidney failure, and it is difficult to get data from them Individuals with congenital esophageal disorders Individuals who participated in a clinical trial within the last 6 months Those who have severe weight gain and it is difficult to get data from them Individuals who do not have personal consent to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Esophageal sphincter pressure. Timepoint: At the beginning of the study (before the intervention), the first week after the intervention, the second week after the intervention, the first month after the intervention, the third month after the intervention and the sixth month after the intervention. Method of measurement: manometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArash Sarveazad
Iran University of Medical Sciences
Outcome results
None listed