Effect of cyclosporine on hair loss of lichen planus

Comparison of the simultaneous effect of oral administration of clobetasol lotion and cyclosporine with the clobetasol lotion alone in the treatment of lichen plano pilaris

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181112041620N1

Enrollment

Registered

2019-03-12

Start date

2018-09-01

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lichen planopilaris. Hair color and hair shaft abnormalities

Interventions

Intervention 1: A lotion of clobetasol as a nosebleed topical steroid once at 30 drops for at least six months. Intervention 2: Oral ciclosporin at a dose of 1 to 3 mg / kg daily plus 30 drops of topi

Eligibility

Sex/Gender

All

Age

15 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with lichen plano pilaris disease at Razi Hospital Age limits of 15 to 40 years

Exclusion criteria

Exclusion criteria: Must be at least one month from the initial referral of these patients to the hospital

Design outcomes

Primary

Measure	Time frame
Plano Polaris's patients percentage. Timepoint: 60days. Method of measurement: Therapeutic questions from the patient.	—

Secondary

Measure	Time frame
Patients may also experience minor problems such as scaling and atrophy due to drug use. Timepoint: 30 days. Method of measurement: Random selection of patients and therapist's questions.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEnsiyeh Yousefi Abdolmaleki

Tehran University of Medical Sciences

ensiyehyousefi@gmail.com+98 21 5560 9951

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026