Effect of low-calorie diet and garlic extract in overweight or obese depressed people

Effect of Low-calorie diet with/without garlic extract supplementation on anthropometric indices and depression status in overweight/obese subjects with major depressive disorder: a clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181111041611N9

Enrollment

Registered

2024-08-07

Start date

2024-08-22

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: depression. Condition 2: Overweight and obesity. Major depressive disorder, single episode, unspecified Overweight and obesity

Interventions

Intervention 1: Intervention group: They will be placed under a low-calorie diet with the use of garlic supplements, so that the patients will receive 800 mg of dry garlic powder in the form of tablet

Eligibility

Sex/Gender

All

Age

20 Months to 50 Months

Inclusion criteria

Inclusion criteria: Patients with mild or moderate depression who are overweight or obese Cooperation and consent to enter the study Age group 20-50 years Not having underlying diseases such as diabetes, endocrine disease, cardiopulmonary disease, liver disease, kidney disease, and thyroid disease

Exclusion criteria

Exclusion criteria: Being under weight loss diets in the last 6 months Pregnancy Lactation Taking steroid, hormonal, and anticoagulant drugs (aspirin, warfarin, heparin, etc.) Taking vitamin, mineral or antioxidant supplements

Design outcomes

Primary

Measure	Time frame
Waist circumference. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: tape measure.;Hip circumference. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: tape measure.;Body mass index. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: Body analyzer.;The amount of adipose tissue. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: body analyzer.;Weight. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: scale.	—

Measure

Time frame

Waist circumference. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: tape measure.;Hip circumference. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: tape measure.;Body mass index. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: Body analyzer.;The amount of adipose tissue. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: body analyzer.;Weight. Timepoint: The beginning and end of the study (the end of the 12th week of the intervention). Method of measurement: scale.

—

Secondary

Measure	Time frame
Depression score in Beck questionnaire. Timepoint: Beginning and end of the study (end of 12 weeks of intervention). Method of measurement: Beck depression questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehnoosh Samadi

Kermanshah University of Medical Sciences

mehnoosh_samadi@yahoo.com+98 83 3837 1706

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026