Effect of Silybum marianum ointment on wound healing and episiotomy pain in primiparous women

Evaluation the effect of Silybum marianum ointment on episiotomy wound healing and pain intesity in primiparous women.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181110041603N1

Enrollment

Registered

2019-08-10

Start date

2019-08-05

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Episiotomy. Disruption of perineal obstetric wound

Interventions

Intervention 1: Intervention group: Silybum marianum ointment (produced in Shahid Beheshti pharmacy faculty) uses topically one finger amount (2cm) on episiotomy wounds twice for 10 days. Interventio

placebo ointment (produced in Shahid Beheshti pharmacy faculty) uses topically one finger amount (2cm) on episiotomy wounds twice for 10 days.

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Being primiparous Aged between 18 to 35 years. BMI between 18.5-29.9. Resident in Talesh. literate. Singleton birth with cephalic presentation Appropriate newborn weight( 2500 to 4000 gr) have a vaginal delivery with mediolateral episiotomy. No long-term rupture membrane more than 24 hours. lack medical disease history. Perineal swelling did not occur immediately after episiotomy. No addiction history No allergies to topical drugs. No manual removal of placenta

Exclusion criteria

Exclusion criteria: Mother's reluctance to continue studying. Mother does not use silybum marianum ointment regularly and in accordance with the instructions. Mother should not wash episiotomy and in accordance with the order (less than twice a day). Mother has sex within 10 days of delivery. Perineal has been tampered with after any episiotomy repair. Excessive bleeding occurs in the first 24 hours of delivery.

Design outcomes

Primary

Measure	Time frame
Intensity of episiotomy pain. Timepoint: before intervention, 12 hours, 5 and 10 days postpartum. Method of measurement: Visual Analogue Scale (VAS).;Wound healing of episiotomy. Timepoint: before intervention, 12 hours, 5 and 10 days postpartum. Method of measurement: REEDA scale.	—

Secondary

Measure	Time frame
Complete episiotomy repair. Timepoint: 10 day after delivery. Method of measurement: REEDA scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sepideh Hajian

Shahid Beheshti University of Medical Sciences

s.hajian@sbmu.ac.ir+98 21 8865 5366

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026