The frozen embryo transfer in infertile women with unsuccessful embryo transfer history.

A clinical trial to compare the frozen embryo transfer (FET) via letrozole and recombinant human FSH (rhFSH) induction with GnRH agonist and estradiol valerate in infertile women with unsuccessful embryo transfer history

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181109041597N1

Enrollment

142

Registered

2019-01-07

Start date

2018-12-22

Completion date

Unknown

Last updated

2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility. Female infertility

Interventions

Intervention 1: Intervention group: The intervention group will receive 2.5 mg of letrozole in cycle day 3 for 5 days and 75 ml of IU rhFSH in cycle day 9. Intervention 2: Control group: The control g

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age range of 22-40 years History of more than twice unsuccessful embryo transfer The male does not have severe infertility

Exclusion criteria

Exclusion criteria: Severe endometriosis stage 3 and 4 Fibroma >4 cm Non-frozen-thawed embryo transfer Necrotic embryonic

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy. Timepoint: Two and six weeks after embryo transfer. Method of measurement: Human chorionic gonadotropin (hCG) test and transvaginal sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElnaz Zohdi

Mashhad University of Medical Sciences

zohdie961@mums.ac.ir+98 51 3853 4021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026