The effect of Bio-impedance Analysis in fluid management of patients on Continuous Renal Replacement Therapy

Clinical evaluation of applying bio-impedance analysis as a guide to detect the appropriate ultrafiltration rate in patients undergoing continuous renal replacement therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181108041595N1

Enrollment

Registered

2019-11-23

Start date

2018-04-19

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: AKI- increase in serum creatinine by at least 0.3 mg/dl within 48 hours or 1.5 times baseline within prior 7 days or urine volume less than 0.5 ml/kg/hour for six hours. Condition 2: Fluid overload:excess fluid in intracellular or extracellular compartments. Acute kidney failure Fluid overload

Interventions

Intervention 1: Intervention group: In patients of this group the volume of fluid removal with ultrafiltration during CRRT is determined based on the results of bio-impedance analysis. Intervention 2

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Admission to the intensive care units of Masih Daneshvari Hospital during the study period Occurring of acute kidney injury Requirement of continuous Renal Replacement Therapy Age of more than 18 years

Exclusion criteria

Exclusion criteria: History of of stage 4 and 5 of chronic kidney disease History of kidney transplantation Cardiorespiratory resuscitation within 24 hours before the start of Renal Replacement Therapy Patient death before 24 hours of starting first Continuous Renal Replacement Therapy History of limb amputation

Design outcomes

Primary

Measure	Time frame
The water content lean body mass. Timepoint: After 72 hours of undergoing CRRT with excluding the time in interruption periods between CRRT sessions. Method of measurement: Records of bioimpedance analyser instrument.	—

Secondary

Measure	Time frame
Urine output. Timepoint: every 8 hors during CRRT. Method of measurement: use of scaled containers.;Mortality rate. Timepoint: At 10th , 30th and 60th day of the study. Method of measurement: Patient are followed for mortality up to 60 days . At the 10th , 30th and 6th day , the mortality is recorded.;Duration of ICU admission. Timepoint: After discharge from the hospital. Method of measurement: Patient's medical files.;Duration of hospital admission. Timepoint: After discharge from the hospital. Method of measurement: Patient's medical files.;Time duration of spending under mechanical ventilation. Timepoint: After discharge from the hospital. Method of measurement: Patient's medical files.	—

Measure

Time frame

Urine output. Timepoint: every 8 hors during CRRT. Method of measurement: use of scaled containers.;Mortality rate. Timepoint: At 10th , 30th and 60th day of the study. Method of measurement: Patient are followed for mortality up to 60 days . At the 10th , 30th and 6th day , the mortality is recorded.;Duration of ICU admission. Timepoint: After discharge from the hospital. Method of measurement: Patient's medical files.;Duration of hospital admission. Timepoint: After discharge from the hospital. Method of measurement: Patient's medical files.;Time duration of spending under mechanical ventilation. Timepoint: After discharge from the hospital. Method of measurement: Patient's medical files.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarin Rashid Farokhi

Shahid Beheshti University of Medical Sciences

f_rashid@sbmu.ac.ir+98 21 2291 5028

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026