Skip to content

Evaluation of efficacy of "Ziziphus Vulgaris" formula to prevent “drug induced liver enzyme disorder” in pulmonary tuberculosis Patients

Evaluation of efficacy of “Ziziphus Vulgaris” formula to prevent “drug induced liver enzyme disorder” in pulmonary tuberculosis Patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181107041586N1
Enrollment
70
Registered
2019-08-10
Start date
2019-07-21
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

drug-induced hepatotoxicity. Toxic liver disease, unspecified

Interventions

Intervention 1: Intervention group: Patients are treated with jujube-based syrup for a month receiving 10 cc of the syrup two times a day, fasting morning and half an hour before bedtime. Routine anti

Sponsors

Sari University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Declaration of written consent of the volunteer for participation in the trial Age from 30 to 65 years A new diagnosis of pulmonary tuberculosis by an infectious disease specialist or a health center doctor No relapse or drug resistance No history of HIV-positive No history of renal failure No history of all types of acute and chronic and alcoholic hepatitis No history of cirrhosis No Pregnancy and lactation

Exclusion criteria

Exclusion criteria: Patients under treatment with other herbal supplements Lack of appropriate verbal communication Patients with Oral intolerance No tendency to take herbal medicine No tendency to consume syrup

Design outcomes

Primary

MeasureTime frame
Serum level of alanine aminotransferase. Timepoint: At the beginning of the study (before the intervention),The end of the second week and at the end of the intervention. Method of measurement: Biochemical tests.;Serum level of aspartate aminotransferase. Timepoint: At the beginning of the study (before the intervention),The end of the second week and at the end of the intervention. Method of measurement: Biochemical tests.;Serum level of Alkalin phosphatase. Timepoint: At the beginning of the study (before the intervention),The end of the second week and at the end of the intervention. Method of measurement: Biochemical tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAssie Jokar

Sari University of Medical Sciences

a.jokar@mazums.ac.ir+98 11 3324 4893

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026