Preterm birth. Onset (spontaneous) of labour before 37 completed weeks of gestation
Conditions
Interventions
Intervention 1: Intervention group: 250 of 17 alpha hydroxyprogesterone caproat weekly immediately after cercelag procedure till 36 weeks of pregnancy. Intervention 2: Intervention group: 400 mg of va
Sponsors
Vice chancellor for research, Hormozgan University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: History of more than two previous preterm birth less than 34 weeks Singleton pregnancy Cervical length less than 25 mm based on latest vaginal sonography
Exclusion criteria
Exclusion criteria: Fetal anomaly Uterine cramp at the time of study Vaginal bleeding at the time of study Preterm rupture of membrane Allergy to hormonal therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of preterm birth. Timepoint: After 34 weeks of pregnancy. Method of measurement: Observational. | — |
Secondary
| Measure | Time frame |
|---|---|
| Gestational age at the time of delivery. Timepoint: At the time of delivery. Method of measurement: Clinical patient record.;Mode of delivery. Timepoint: At the time of delivery. Method of measurement: Clinical patient record.;Newborn weight. Timepoint: Immediately after delivery. Method of measurement: Clinical patient record.;Newborn apgar. Timepoint: Immediately after delivery. Method of measurement: Newborn clinical record.;Incidence of newborn respiratory distress syndrome. Timepoint: At birth and 28 days after birth. Method of measurement: Newborn clinical record.;Incidence of newborn sepsis. Timepoint: At birth and 28 days after birth. Method of measurement: Newborn clinical record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmene Ranjbar
Hormozgan University of Medical Sciences
Outcome results
None listed