Effect of erythropoietin on level of consciousness of brain trauma patients admitted to intensive care unit

Clinical trial to compare the effect of erythropoietin and normal saline on level of consciousness of brain trauma patients admitted to intensive care unit

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181104041551N3

Enrollment

Registered

2020-09-16

Start date

2020-08-21

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain trauma patients admitted to the ICU. Focal traumatic brain injury

Interventions

Intervention 1: Intervention group: The intervention group will receive 4000 units of subcutaneous erythropoietin made by Pooyesh Daroo Company with a volume of half a cc on days 1, 3 and 5. Intervent

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with brain trauma with moderate GCS (7-12) The first 24 hours after trauma Expected time for the duration of hospitalization, at least 48 hours

Exclusion criteria

Exclusion criteria: History of deep vein thrombosis, pulmonary embolism or any thromboembolic event Erythropoietin treatment in the last 30 days Systolic blood pressure =160 History of heart failure History of cancer Neurosurgery elective surgery

Design outcomes

Primary

Measure	Time frame
Level of conciousness. Timepoint: Daily until 14 days. Method of measurement: Glasgow Coma Scale and SOFA four-point scale.;Deep vein thrombosis. Timepoint: Daily. Method of measurement: Daily visit of the limbs.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Fatemeh Heydari

Mazandaran University of Medical Sciences

f.heydari@mazums.ac.ir+98 11 3336 1701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026