Antimicrobial efficacy of Allium Sativum extract as endodontic irrigant

Evaluation of antimicrobial efficacy and flare up incidence of Allium Sativum L. extract as an endodontic irrigant following instrumentation in infected teeth: a single blind clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181103041534N1

Enrollment

Registered

2018-12-24

Start date

2018-11-09

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

necrosis of pulp. Necrosis of pulp

Interventions

Intervention 1: Intervention group: use of Allium sativum L. as an endodontic irrigant. Intervention 2: Control group: use of sodium hypochlorite az an endodontic irrigant.

Eligibility

Sex/Gender

All

Age

10 Years to No maximum

Inclusion criteria

Inclusion criteria: patients referring to Mashhad Faculty of dentistry permanent teeth one canal teeth with necrotic pulp teeth with chronic apical periodontitis

Exclusion criteria

Exclusion criteria: teeth with calcified pulp chamber patients with immune-suppresive disease taking antibiotic before or during treatment teeth that can not be isolated with rubber dam

Design outcomes

Primary

Measure	Time frame
Measuring microbial load in each tooth using CFU(colony forming units). Timepoint: The beginig of the study (before intervention) and 3 days after the interventuon. Method of measurement: Microbial culture and colony forming units count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJamile? Ghoddusi

Mashhad University of Medical Sciences

ghoddusij@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026