The Effects of Tranexamic Acid and Vitamin K in the prevention of hemorrhage in TURP surgery.

Comparison of the effects of Tranexamic Acid and Vitamin K in the prevention of hemorrhage in TURP surgery.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181031041515N1

Enrollment

Registered

2019-06-01

Start date

2018-11-06

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign prostate Hyperplasia. Enlarged prostate

Interventions

Intervention 1: Intervention group: Ampol of 1 vial of Transamin 500 mg (Caspian Company Rasht Drug) will be injected into the serum during an operation in the Tranexamic Acid group. Intervention 2: I

Eligibility

Sex/Gender

Male

Age

60 Years to 90 Years

Inclusion criteria

Inclusion criteria: Male gender 60 to 90 year-old Satisfaction for performing TURP surgery

Exclusion criteria

Exclusion criteria: Coagulation disorders (hemophilia and ...) Liver Disease (Cirrhosis and ...) Uses of anticoagulant medication (Warfarin and Heparin and Plavix) History of heart disease History of thrombotic stroke

Design outcomes

Primary

Measure	Time frame
Bleeding status after TURP surgery. Timepoint: Within 48 hours after surgery. Method of measurement: Volume of fluid in the urethra for hematuria, the amount of hemoglobin before and after surgery.	—

Secondary

Measure	Time frame
The amount of bleeding during and after the TURP operation. Timepoint: During and after the TURP operation. Method of measurement: Hemoglobin level and serum volume of used washing.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYousef Kolookhi

Islamic Azad University

dryousefkolookhianestezi@gmail.com+98 23 3224 2487

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026