Endometriosis. Endometriosis
Conditions
Interventions
Intervention 1: Intervention group: Patients with endometriosis who will be given dopamine agonists (cabergoline) 0.5 milligrams twice a week for three months. Intervention 2: Control group: Patients
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Diagnosis of clinical endometriosis by observing pain and tenderness in the pelvic examination along with endometriosis nodules in the vaginal examination, firm and motionless uterus and confirmed by ultrasound or MRI (observation of endometriosis cysts and nodules) Diagnosis of grade I-IV endometriosis based on r-ASRM criteria during diagnostic laparoscopy during the previous 12 months Dysmenorrhea complaint with EAPP score >30 or >40 Normal pap smear
Exclusion criteria
Exclusion criteria: Endometriosis treated less than 6 months ago with a GNRH agonist or less than 3 months ago danazol or progesterone tablets or less than 1 month ago with oral contraceptives. Severe pain unrelieved by Cabergoline necessitating the use of other analgesics lack of willingness to continue in the study non-adherence to the treatment regimen any adverse reactions to the medication (particularly allergies) Sensitivity to the medication and incorrect medication intake in the control group
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severe dysmenorrhea pain. Timepoint: On the first day of menstruation and at the end of the first, second and third month of treatment. Method of measurement: By 10-point visual analogue scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElahe Khaleghzadeh
Mashhad University of Medical Sciences
Outcome results
None listed