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Comparison of pregnancy rates in simultaneous 3 and 5-day embryo transfer with 5-day embryo transfer in patients with a history of recurrent implantation failure

Comparison of Pregnancy Rate in Mixed double embryo transfer (MDET) with Transfer single blastocyst Embryo transfer (SBET) in Recurrent Implantation Failure (RIF)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181030041503N5
Enrollment
126
Registered
2021-12-11
Start date
2021-09-23
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Complications of attempted introduction of embryo in embryo transfer

Interventions

Intervention 1: Intervention group: On the day of transfer, one cleavage-stage embryo that thawed the same day and one Blast stage embryo that thawed 2 days before and reached the blast stage

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 42 Years

Inclusion criteria

Inclusion criteria: Infertile women (18-42 years) with a history of at least two failed embryo transfers and at least two good-quality embryos have been transferred.• There are at least two 3-day-old freezers with grade 1 or 2• Normal couple karyotype• Lack of uterine abnormalities and thrombophilic disorders

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy rate. Timepoint: 2 week after embryo transfer. Method of measurement: BHCG serum.;The rate of clinical pregnancy. Timepoint: 6 weeks after embryo transfer. Method of measurement: Sonography.;Ongoing pregnancy. Timepoint: Continue pregnancy for up to 12 weeks. Method of measurement: Transvaginal ultrasound.

Secondary

MeasureTime frame
Rate of miscarriage. Timepoint: Before 20 weeks of pregnancy. Method of measurement: Bleeding and expulsion of the fetus.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaliheh Mahmoudinia

Mashhad University of Medical Sciences

mahmoudiniam@mums.ac.ir+98 51 3853 4021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026