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Comparison of embryo transfer in two different protocol

Comparison of the consequences of freezing embryo transfer in infertile women with tamoxifen and recombinant gonadotropin group with GNRH agonist group and estradiol valerate

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181030041503N3
Enrollment
96
Registered
2020-06-25
Start date
2019-05-22
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Complications of attempted introduction of embryo in embryo transfer

Interventions

Intervention 1: The intervention group included 96 patients who were given 20 mg of tamoxifen twice daily for the third day of the cycle for five days, and HMG was given at 150 mg daily on days 6 and

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 42 Years

Inclusion criteria

Inclusion criteria: Infertile women (18-42 years old) who go to Milad Infertility Center for transfer freezing embryo with a history of two or more failed embryo transfer. Couples who are not severely infertile or TESE candidate (Testicular Sperm Extrection) . may not have severe grade 3 and 4 endometriosis. may not have fibroids> 4 cm. may not be candidates for fresh embryo transfer. and may not have primary and secondary amenorrhea.

Exclusion criteria

Exclusion criteria: Failure to remove the fetus from the freezer, , necrotic embryo patient dissatisfaction during treatment to continue the study

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy rate. Timepoint: 2 week after embryo transfer. Method of measurement: BHCG.;The rate of clinical pregnancy. Timepoint: 6 weeks after embryo transfer. Method of measurement: Sonography.

Secondary

MeasureTime frame
Ongoing pregnancy. Timepoint: Continue pregnancy for up to 12 weeks. Method of measurement: Transvaginal ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaliheh Mahmoudinia

Mashhad University of Medical Sciences

MahmoudiniamM@mums.ac.ir+98 51 3853 4021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026