Skip to content

Comparison of the effect of “paracetamol-lidocaine” and “fentanyl-midazolam” on perioperative pain and hemodynamic changes in patients undergoing cataract surgery

Comparison of the effect of “paracetamol-lidocaine” and “fentanyl-midazolam” on perioperative pain and hemodynamic changes in patients undergoing cataract surgery under topical anesthesia :A randomized double blind clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181027041480N1
Enrollment
80
Registered
2019-05-02
Start date
2019-06-21
Completion date
Unknown
Last updated
2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract. Senile cataract, unspecified

Interventions

Intervention 1: Intervention group: in the A group ( Lidocaine +Parastomal ), we inject 0.2 milligram/kg Lidocaine in the operating room and infusion of 1-g Parastomal in 100 cc normal saline preoper

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: patients aged 50-80 years old ASA class 1 & 2 scheduled for cataract surgery Satisfaction to participate and collaborate in the study

Exclusion criteria

Exclusion criteria: History of seizure Allergy to any of the study medications Hypertension Psychosis history of use of narcotics Mentally challenged patients

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Immediately after surgery and after the condition of the patient stabilizes in recovery. Method of measurement: Verbal pain scale and visual analogue scale.;Mean arterial pressure. Timepoint: Before take the medicine, 5 and 15 minutes after drug injection and before and after Cutting Surgery. Method of measurement: Monitoring full parameter Pooyandegan Rah Saadat.;Heart rate. Timepoint: Before take the medicine, 5 and 15 minutes after drug injection and before and after Cutting Surgery. Method of measurement: Monitoring full parameter Pooyandegan Rah Saadat.;Respiratory rate. Timepoint: Before take the medicine, 5 and 15 minutes after drug injection and before and after Cutting Surgery. Method of measurement: Monitoring full parameter Pooyandegan Rah Saadat.;Sedasion. Timepoint: Before take the medicine, 5 and 15 minutes after drug injection and before and after Cutting Surgery. Method of measurement: Sedation score (score 1: movement of head and neck , score 2: brief movement of hands, score 3: whining the patient, score 4: complete relaxation).

Secondary

MeasureTime frame
Postoperative complications ( Headache, nausea and vomiting, chills, respiratory depression). Timepoint: After surgery and during admission. Method of measurement: Questionnaire and patient file.;Patient satisfaction in anesthesia. Timepoint: After surgery and during admission. Method of measurement: Questionnaire and patient file.;Amount of Propofol and narcotic consumption. Timepoint: During the hospitalization. Method of measurement: Patient file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRahele Safaie

Qazvin University of Medical Sciences

rahi_s29@yahoo.com+98 28 3376 0620

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026