Study of Royal jelly effect on serum levels of cytokines and antioxidant capacity on Multiple sclerosis patients in comparison with Omega-3

Study of Royal jelly effect on serum levels of IL-4, TNF- a,TGF-B, IFN-? cytokines and its antioxidant capacity on Multiple sclerosis patients in comparison with Omega-3

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181026041466N4

Enrollment

Registered

2020-09-16

Start date

2019-05-20

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: Control group: Interferon (main treatment) with Omega-3 capsules (1 g daily) for one month. One capsule (made by Nature co) daily after breakfast. Intervention 2: Intervention group:

Eligibility

Sex/Gender

All

Age

15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with multiple sclerosis with fatigue No other neurological diseases No new attack in the last month No Diseases like diabetes and autoimmune diseases

Exclusion criteria

Exclusion criteria: Pregnancy

Design outcomes

Primary

Measure	Time frame
Interferon Gama. Timepoint: first day of tial and one month later. Method of measurement: kits for measuring the Interferon Gama.;Transforming growth factor beta?. Timepoint: first day of tial and one month later. Method of measurement: Measuring kits for measuring the TGF-B.;Tumor necrosis factor alpha. Timepoint: first day of tial and one month later. Method of measurement: Measuring kits for measuring the TNF-a.;Interlukin-4. Timepoint: first day of tial and one month later. Method of measurement: Measuring kits for measuring the IL-4.;Antioxidant capacity. Timepoint: first day of tial and one month later. Method of measurement: Frap Test.	—

Measure

Time frame

Interferon Gama. Timepoint: first day of tial and one month later. Method of measurement: kits for measuring the Interferon Gama.;Transforming growth factor beta?. Timepoint: first day of tial and one month later. Method of measurement: Measuring kits for measuring the TGF-B.;Tumor necrosis factor alpha. Timepoint: first day of tial and one month later. Method of measurement: Measuring kits for measuring the TNF-a.;Interlukin-4. Timepoint: first day of tial and one month later. Method of measurement: Measuring kits for measuring the IL-4.;Antioxidant capacity. Timepoint: first day of tial and one month later. Method of measurement: Frap Test.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Aghaei

Ahvaz University of Medical Sciences

ali.aghaei110@gmail.com+98 61 3333 8149

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026