The comparison of Rupivacain versus Lidocain effect on intraoperative bleeding and pain, and postoperative pain after wisdom tooth surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181023041425N3

Enrollment

Registered

2021-12-06

Start date

2021-12-31

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Acute pain. Condition 2: intraoperative bleeding. Acute pain, not elsewhere classified Hemorrhage, not elsewhere classified

Interventions

Intervention 1: Intervention group: includes group that received 2cc Ropivacaine 0/5% (naropin) as preoperative anesthesia. Intervention 2: Control group: includes group that received 1/8cc Lidocaine

Eligibility

Sex/Gender

All

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: According to the ASA physical status classification system, patient should be ASA I or ASA II (normal healthy patient or patient with mild systemic disease) Patient with informed consent. Patient's age should be between 18-30 years. Patients should have two wisdom teeth (classified in the same class by Pell & Gregory; mesioangular impaction, level B, class 1 or 2), which are similar in terms of surgical severity No general contraindications (patients with low blood pressure, bradycardia, sinus disorder, unstable high blood pressure, arousability, tachyphylaxis and liver disorders.) No lesions and malignancies at the surgical site; No smoking.

Exclusion criteria

Exclusion criteria: Patient with wisdom tooth surgery on one side Patient who needs more than one cartridge injection Occurring medical problems during surgery; Surgery lasting more than 20 minutes.

Design outcomes

Primary

Measure	Time frame
Evaluate the amount of pain after surgery. Timepoint: 2 hour, 6 hours, 12hours, 18 hours, and 24 hours postoperatively. Method of measurement: Visual analogue scale (VAS) for pain.;The amount of surgical bleeding. Timepoint: at the end of surgery. Method of measurement: Blood in suction and gauze.;Evaluate the amount of pain during surgery. Timepoint: After flap removal, after osteotomy, and after tooth extraction. Method of measurement: Visual analogue scale (VAS) for pain.	—

Measure

Time frame

Evaluate the amount of pain after surgery. Timepoint: 2 hour, 6 hours, 12hours, 18 hours, and 24 hours postoperatively. Method of measurement: Visual analogue scale (VAS) for pain.;The amount of surgical bleeding. Timepoint: at the end of surgery. Method of measurement: Blood in suction and gauze.;Evaluate the amount of pain during surgery. Timepoint: After flap removal, after osteotomy, and after tooth extraction. Method of measurement: Visual analogue scale (VAS) for pain.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Hosseini Abrishami

Mashhad University of Medical Sciences

hoseiniabrishamim@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026