Evaluation of grape seed extract effect on oral mucositis in patients with a history of head and neck radiotherapy

Evaluation of adjunctive effect grape seed extract(GSE) on oral mucositis in patients with a history of head and neck radiotherapy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181022041418N1

Enrollment

Registered

2019-06-03

Start date

2019-04-11

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Radiation Mucositis. Oral mucositis (ulcerative) due to radiation

Interventions

Intervention 1: Intervention group:25 patients whom will be treated under head and neck radiotherapy are being recognized and they receive 2% grape seed extract mouth wash which has been produced by

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Complete consciousness Ability of reading and writing Oral mucus healthy Total radiation more than 60gray in radiotherapy duration and 2gray radiation everyday

Exclusion criteria

Exclusion criteria: Respiratory system diseases and asthma Diabetes Autoimmune diseases Fever and Neutropenia Continuous usage of analgesics Narcotic drug usage Antibiotics usage Using another mouthwash during investigation Chemotherapy during investigation

Design outcomes

Primary

Measure	Time frame
Mucositis intensity. Timepoint: First-5th-10th-14th days after mouthwash using. Method of measurement: Mucositis grading 0-4.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Hossein Eslami

Tabriz University of Medical Sciences

eslamihosein56@yahoo.com+98 41333559659

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026