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The effect of intravenous trehalose on Fatigue in MS

Investigating the effect of intravenous Trehalose on the fatigue and performance of a patient with Multiple Sclerosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181022041407N14
Enrollment
1
Registered
2025-06-19
Start date
2025-09-23
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. G35

Interventions

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of multiple sclerosis (MS) Suffering from fatigue Satisfaction for participation in the research project Living in Mashhad

Exclusion criteria

Exclusion criteria: Willingness to withdraw from the study Exacerbation of manifestations of MS after each IV administration Under treatment for depression

Design outcomes

Primary

MeasureTime frame
Fatigue score. Timepoint: At baseline and after 12 weeks. Method of measurement: Using Modified Fatigue Impact Scale (MFIS).

Secondary

MeasureTime frame
Quality of life. Timepoint: At baseline and after 12 weeks. Method of measurement: Using European Quality of Life 5 Dimensions 3 Level Version (EQ-5D-3L).;Depression and anxiety. Timepoint: At baseline and after 12 weeks. Method of measurement: Using Hospital Anxiety and Depression Scale (HADS).;Ability to walk. Timepoint: At baseline and after 12 weeks. Method of measurement: Multiple Sclerosis Walking Scale-12 (MSWS-12).;Inflammatory markers including C-reactive protein, gene expression of TNFa, IFN?, IL10, IL16, IL17). Timepoint: At baseline and after 12 weeks. Method of measurement: Blood Sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Emadzadeh

Mashhad University of Medical Sciences

maryamemadzadeh@yahoo.com+98 51 3841 7403

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026