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Investigation the effect of trehalose on Rheumatoid Arthritis

Investigation the role of trehalose on symptoms of a patient with Rheumatoid Arthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181022041407N13
Enrollment
1
Registered
2024-10-20
Start date
2024-10-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis. Other rheumatoid arthritis

Interventions

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient with Rheumatoid Arthritis diagnosis (according to ACR/EULAR) DAS28 > 2.5 (after 3 months of 7.5 mg methotrexate and 5 mg prednisolone) Satisfaction for participation in the research project

Exclusion criteria

Exclusion criteria: Uncontrolled and severe adverse event Unwilling to continue the research project

Design outcomes

Primary

MeasureTime frame
Assessment of disease activity. Timepoint: Baseline and after 12 weeks. Method of measurement: Disease Activity Score (DAS28).;Measure change in rheumatoid arthritis symptoms. Timepoint: Baseline and after 12 weeks. Method of measurement: ACR (American College of Rheumatology) score.

Secondary

MeasureTime frame
Quality of life. Timepoint: Baseline and after 12 weeks. Method of measurement: Health Assessment Questionnaire-Disability Index (HAQ-DI).;Assessment of Disease Activity. Timepoint: Baseline and after 12 weeks. Method of measurement: US-7 score (by ultrasonography of seven preselected joints).;Erythrocyte Sedimentation Rate (ESR). Timepoint: Baseline and after 12 weeks. Method of measurement: Blood test.;C-reactive protein. Timepoint: Baseline and after 12 weeks. Method of measurement: Blood test.;Interleukin 6 (IL6). Timepoint: Baseline and after 12 weeks. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Emadzadeh

Mashhad University of Medical Sciences

maryamemadzadeh@yahoo.com+98 51 3841 7403

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026