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The effective of opioid-ketamine on pain relief in traumatic patients

A clinical trial to compare the effectiveness of opioid with opioid-ketamine on pain relief in traumatic patients

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181021041399N1
Enrollment
80
Registered
2018-11-07
Start date
2018-11-22
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Traumatic arthropathy. Condition 2: injuries of head. Condition 3: Injury of abdominal. Condition 4: Injury of hand region. Condition 5: Injury of hand leg. Traumatic arthropathy Other and unspecified injuries of head Injury of abdominal aorta Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand Traumatic amputation of one foot and other leg [any level, except foot]

Interventions

Intervention 1: Control group: who is receiving 20 mg opioid with distilled water. Intervention 2: Intervention group: who is receiving 10 mg opioid with 0.1 mg/kg ketamine.

Sponsors

Artesh University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Aged between 15 and 40 years Having a natural intelligence No speech problem according to the diagnosis patients with trauma require the analgesic

Exclusion criteria

Exclusion criteria: Allergy to the drugs studied Having underlying disorder of respiratory, cardiac, neurological Addicted Active psychosis Poisoning clinical

Design outcomes

Primary

MeasureTime frame
Pain relief. Timepoint: before, 15 and 30 minutes. Method of measurement: visual analog scale.

Secondary

MeasureTime frame
Side-effects of medications (nausea and vomiting, dizziness, dry mouth, euphoria, skin rash in the area of injection, nystagmus, tinnitus, etc). Timepoint: before, 15 and 30 minutes after intervention. Method of measurement: Designed questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Arzani Shams Abadi

Artesh University of Medical Sciences

me_arzani@yahoo.com+98 21 3321 6512

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026