The Efficiency of Probiotic on Helicobacter Pylori Eradication

The Efficiency of Probiotic on Helicobacter Pylori Eradication, a Retrospective Parallel Group Double-Blind, Placebo-Controlled Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181015041349N1

Enrollment

100

Registered

2019-02-09

Start date

2015-05-21

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect of Probiotic on Eradication of H.pylori Infection.

Interventions

Intervention group: Probiotic (saccharomyces boulardii (250 mg, 1010 viable cells/g).Two weeks, twice per day..

Eligibility

Sex/Gender

All

Age

18 Years to 63 Years

Inclusion criteria

Inclusion criteria: patients with aged 18-63 years participants who their contamination were confirmed through histology, serum anti-H. pylori IgG, or stool antigen tests.

Exclusion criteria

Exclusion criteria: The exclusion criteria were taking antibiotics, bismuth component, proton pump inhibitor (PPI), and H2Blocker in the recent 2-3 months. Pregnant women as well as patients with previous history of GI surgery or having concurrent severe disease during the time of experiment also been excluded.

Design outcomes

Primary

Measure	Time frame
Eradication of H.pylori Infection. Timepoint: before intervention and 8 weeks later (after follow-up). Method of measurement: histology, serum anti-H. pylori IgG, or stool antigen tests.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Jalil Masoumi

Shiraz University of Medical Sciences

sjm@sums.ac.ir+98 71 3233 2771

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026