Effect of Melatonin in treatment of Pediatric Status Epilepticus

Evaluation of The Effect of Melatonin on Treatment of Pediatric Refractory and Super-Refractory Generalized Convulsive Status Epilepticus in 1 to 15 years old Children

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181014041338N2

Enrollment

Registered

2023-01-22

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric status epilepticus. Other generalized epilepsy and epileptic syndromes, intractable, with status epilepticus

Interventions

Intervention 1: Intervention group:. Intervention 2: Control group:.

Eligibility

Sex/Gender

All

Age

1 Years to 15 Years

Inclusion criteria

Inclusion criteria: 1 to 15 years old children admitted in Namazi hospital PICU diagnosed with refractory and super-refractory generalized convulsive status epilepticus

Exclusion criteria

Exclusion criteria: Dissent of patient's legal guardian regarding administration of melatonin. Inability to use NG tube for any reason. Occurrence of adverse drug reaction to melatonin.

Design outcomes

Primary

Measure	Time frame
Cessation of generalized convulsive status epilepticus. Timepoint: Continuous 24-hour monitoring from the moment the patient enters the pediatric intensive care unit. Method of measurement: Clinical observation by PICU's attending physician and staff.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Nemati

Shiraz University of Medical Sciences

meshham5@gmail.com+98 71 3647 4332

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026