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The effectiveness of oral minoxidil in women with scalp hair loss

A triple-blind randomized clinical trial on the effectiveness of oral minoxidil in the treatment of women with Androgenetic Alopecia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181011041311N1
Enrollment
60
Registered
2019-03-09
Start date
2018-12-22
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female pattern hair loss (FPHL) androgenic alopcia. Androgenic alopecia

Interventions

Intervention 1: Intervention group: Daily treatment with Oral Minoxidil Tablets (0.25 mg) and topical Placebo (1 CC twice a day) for one year. Intervention 2: Control group: Daily treatment with topic

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women with female pattern hair loss androgenic alopcia ( with sinclair stgae between 2 and 5) based on clinical diagnosis and histopathology Age: between 18 and 50

Exclusion criteria

Exclusion criteria: Other causes of hair loss, including inflammatory and cicatricial hair loss The presence of other symptoms of hyperandrogenism (in particular, malaise and hirsutism), which is also evident in laboratory examination of hormonal disorders supported by polycystic ovaries, ovarian and adrenal tumors. Severe systemic disease (cardiovascular - renal - hepatic) A history of pressure drop or blood pressure less than 90/60 mmHg The patient's desire for pregnancy during one year is under study Taking any effective medication for alopecia, including hormonal medications

Design outcomes

Primary

MeasureTime frame
Hair loss condition. Timepoint: Every 3 months. Method of measurement: based on Sinclair scale and shedding scale.;Evaluating the density and thickness of the hair. Timepoint: Every 3 months. Method of measurement: By trichoscopy.

Secondary

MeasureTime frame
Blood pressure, weight. Timepoint: Weekly up to one month then monthly up to three months and then every three months. Method of measurement: Pressure gauge cuff, Weight gauge.;Liver, renal and electrolyte tests. Timepoint: The third and 12th month after starting treatment. Method of measurement: Blood sampling.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahideh Saabeti

Mashhad University of Medical Sciences

sabetiv@yahoo.com+98 51 3849 4720

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026