The effects of laxative drugs in the treatment of acute constipation in patients with acute stroke

Comparison of response to two regimens of Lactolose and Bisacodyl in the treatment of acute constipation in patients with acute stroke

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181009041286N1

Enrollment

Registered

2019-01-17

Start date

2017-12-22

Completion date

Unknown

Last updated

2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute constipation. Constipation

Interventions

Intervention 1: Intervention group (Bisacodyl): Patients will receive 10 mg daily and will be evaluated for at least 5 days for response to treatment. Intervention 2: Control group (Lactulose): Patien

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Admission within 48 hours of onset of symptoms Definite stroke diagnosis and confirmation with CT-Scan or MRI Acute constipation

Exclusion criteria

Exclusion criteria: Patients with constipation before stroke History of colon or rectum cancer Constipation caused by metabolic disorder such as hypokalemia Taking drugs that cause constipation, such as anticholinergic drugs or drugs with anticholinergic effects, calcium blockers, etc. History of diabetes mellitus History of myocardial infarction History of hypothyroidism

Design outcomes

Primary

Measure	Time frame
Defication. Timepoint: Daily check for defication after taking drug. Method of measurement: Questionnaire designed by researcher.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Daneshvar kakhki

Kashan University of Medical Sciences

daneshvar-r@mail.kaums.ac.ir+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026