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Investigating the effect of standard dose of Albuterol nebulizer, low dose of Albuterol nebulizer with Ipratropium bromide and Albuterol spray on the QT interval in children with moderate to severe asthma.

Investigating the effect of standard dose of Albuterol nebulizer, low dose of Albuterol nebulizer with Ipratropium bromide and Albuterol spray on the QT interval in children with moderate to severe asthma.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181006041252N5
Enrollment
81
Registered
2019-01-04
Start date
2018-11-19
Completion date
Unknown
Last updated
2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. Asthma

Interventions

Intervention 1: Intervention group: Patients use a standard dose of inhaler Albuterol (15 mg/kg, maximal 2.5 mg) twice every 20 minutes to 3 times. Intervention 2: Intervention group: Patients use a c

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Months to 15 Years

Inclusion criteria

Inclusion criteria: Children aged 6 months to 15 years Children with moderate to severe asthma or pulmonary obstructive disorder are more than 6 months old Children whose forced Expiratory Volume in First Second (FEV1) is less than 80%

Exclusion criteria

Exclusion criteria: Children with heart and kidney disease Children who have received Albuterol treatment for less than 30 days. Children who have used Systemic Corticosteroids in the last week

Design outcomes

Primary

MeasureTime frame
QT interval in the electrocardiogram. Timepoint: Electrocardiography (ECG) is performed at the beginning of the study (before the intervention), after the end of the third treatment and 4 hours after the treatment. Method of measurement: Electrocardiography (ECG).

Countries

Iran (Islamic Republic of)

Contacts

Public Contact?Dr. Alireza Asadi

Sabzevar University of Medical Sciences

dralirezaasadi@gmail.com+98 51 4401 1604

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026