The effect of three types of aerobic, resistance, and topical specialized exercises in diabetic patients

Comparison of the effect of three types of aerobic, resistance, and topical specialized exercises on glycemic indexes and neuropathy in diabetic patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181006041252N19

Enrollment

Registered

2019-12-17

Start date

2019-04-14

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic neuropathy. Diabetes mellitus due to underlying condition with diabetic neuropathy, unspecified

Interventions

Intervention 1: The first Intervention group: Patients in this group perform resistance training for 8 weeks and 3 sessions per week including 10 minutes of warm-up, 40 minutes of core exercise, and 1

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: FBS above 126 mg/dl or 2h blood glucose above 200 mg/dl Diabetic neuropathy Having diabetes for 4-6 years History of Metformin use for at least 2 years Start medication for diabetes

Exclusion criteria

Exclusion criteria: Having autonomic neuropathy, non-diabetic neuropathy Using drugs affecting the nervous and vascular systems Having Cardiac or musculoskeletal problems precludes activity

Design outcomes

Primary

Measure	Time frame
Fasting blood sugar (FBS). Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of Luminescence quantitative and ELISA methods.;Hemoglobin A1C. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of Luminescence quantitative and ELISA methods.;The severity of diabetic neuropathy. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of the Michigan Neuropathy Screening Instrument (MNSI).	—

Measure

Time frame

Fasting blood sugar (FBS). Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of Luminescence quantitative and ELISA methods.;Hemoglobin A1C. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of Luminescence quantitative and ELISA methods.;The severity of diabetic neuropathy. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of the Michigan Neuropathy Screening Instrument (MNSI).

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Secondary

Measure	Time frame
The limbs blood flow. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Ankle-Brachial Index (ABI) device.;Dynamic equilibrium. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Neuron-EMG-Micro device.;The sense of vibration. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Tuning fork device.;The sense of touch. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Round bottom pin, cotton or brush.	—

Measure

Time frame

The limbs blood flow. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Ankle-Brachial Index (ABI) device.;Dynamic equilibrium. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Neuron-EMG-Micro device.;The sense of vibration. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Tuning fork device.;The sense of touch. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Round bottom pin, cotton or brush.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sahebkar

Sabzevar University of Medical Sciences

Mohammad.sahebkar66@yahoo.com+98 51 4401 8337

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026