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Comparison of the efficacy of two medicinal diets for the eradication of Helicobacter pylori.

Comparison of quadruple diet containing levofloxacin with quadruple diet containing clarithromycin for eradication of Helicobacter as the first line of treatment

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181006041252N18
Enrollment
400
Registered
2019-12-03
Start date
2019-03-21
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group: Patients in this group are treated with a quadruple regimen for 2 weeks: 1. Levofloxacin 500 mg twice daily 2. Bismuth subcitrate 120 mg four times daily 3. Amoxici

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Helicobacter pylori infection in urea breath test Patients with symptoms of dyspepsia Patients who underwent upper endoscopy and had a positive rapid urease test.

Exclusion criteria

Exclusion criteria: Pregnancy Unwillingness to enter the study Previous history of allergy to any medication Patients who have previously been treated for Helicobacter pylori infection. Patients who have been taking Proton-pump inhibitors (PPIs) or antibiotics for the past 4 weeks

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori infection. Timepoint: At the beginning of the study (before the intervention) and 4 weeks after starting the treatment. Method of measurement: Endoscopic biopsy and urea breathing test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sahebkar

Sabzevar University of Medical Sciences

Mohammad.sahebkar66@yahoo.com+98 51 4401 8337

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026