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Evaluation of the effect of amniotic membrane on wound healing

Evaluation of human amniotic membrane on wound healing of donor site in burn patients compared with standard treatment

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181006041252N14
Enrollment
35
Registered
2019-08-26
Start date
2016-04-20
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn. Calcification and ossification of muscles associated with burns, unspecified site

Interventions

Intervention 1: Intervention group: donor site in this group was covered with amniotic membranes made by Royan Cells Co 10 x 15 cm, Vaseline gauze, and wet dressing. Intervention 2: Control group: The

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 2-60 years Grade 2 and 3 burn patients require autologous skin graft (STSG) and surgery

Exclusion criteria

Exclusion criteria: Connective tissue diseases, diabetes, malnutrition, septicemia, heart disease, kidney failure, cancer, chemotherapy and the use of corticosteroid drugs. Dissatisfaction patients to participate in the study.

Design outcomes

Primary

MeasureTime frame
Determination of pigmentation. Timepoint: Measurement of pigmentation on days 10, 20 and 30 after the intervention. Method of measurement: Photographic Morphometry.;Determination of epithelization. Timepoint: Measurement of epithelization on days 10, 20 and 30 after the intervention. Method of measurement: Photographic Morphometry.;Determination of superficial vascularity. Timepoint: Measurement of superficial vascularity on days 10, 20 and 30 after the intervention. Method of measurement: Photographic Morphometry.;Determination of granulation. Timepoint: Measurement of granulation on days 10, 20 and 30 after the intervention. Method of measurement: Photographic Morphometry.

Secondary

MeasureTime frame
Determine the amount of pain. Timepoint: Measurement of pain on days 10, 20 and 30 after the intervention. Method of measurement: Visual Analogue Scale of Pain Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sahebkar

Sabzevar University of Medical Sciences

Mohammad.sahebkar66@gmail.com+98 51 4401 8337

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026