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Therapeutic effect of ointment containing extract of Arbenia Euchromia plant and amniotic membrane in burn wound

Assessing therapeutic effects of a topical ointment containing the extract of Arnebia euchroma and amniotic membrane in patients with burn; a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181005041243N4
Enrollment
60
Registered
2024-07-08
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn wound.

Interventions

Intervention group: Ointment name: Arnebia euchroma, chemical composition and its concentration: extracts are prepared by soaking plant materials in (67%-EtOH) under ultrasound at room temperature. Th

Sponsors

Iranian academic center for education culture and research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: age between 18-60 Burns due to contact with hot liquids or heat sources, patients with second degree burns according to the criteria determined according to the reference sources as follows: 1. The surface of the burn is red or pink in color. 2- It has a moist surface with liquid oozing or accompanied by blisters. 3- Having extreme sensitivity when touching The extent of the burn wound is between 1 and 10%, which is determined based on the criteria of Lund and Browder Less than 6 hours should pass from the occurrence of the burn to the time the patient goes to the treatment center The patient's wound was free of infection and trauma The wound of the patient should be only on the limbs and trunk and not in the head, face and genital area.

Exclusion criteria

Exclusion criteria: Suffering from diseases such as anemia, diabetes, malignancies and immune system defects due to the impact on the wound healing process. Taking drugs that weaken the immune system and are effective on wound healing, such as steroid drugs - substance abuse The patient's unwillingness to continue participating in the research or not returning to the treatment center Damage to the burn wound during the intervention, chemotherapy or radiation therapy during the research and showing signs of sensitivity to 1% silver sulfadiazine or the study drug during the intervention pregnancy

Design outcomes

Primary

MeasureTime frame
Determining the extent of the wound and the time required to heal the wound. Timepoint: At the beginning of the study (before the start of the intervention) and 14 days after starting to use ointments. Method of measurement: The size of the wound is determined by a ruler and the time required to heal the wound is determined by a doctor's visit.

Secondary

MeasureTime frame
Edema; hematoma; itching; pain; infection. Timepoint: At the beginning of the study (before the start of the intervention) and 14 days after starting to use ointments. Method of measurement: doctor's opinion.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Nasimi

Tehran University of Medical Sciences

nsm.maryam@gmail.com+98 21 5563 0553

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026