Efficacy of adjuvant Nd-Yag in acne

The efficacy of adjuvant Nd-Yag laser in the long-term treatment of moderate inflammatory acne and its effect on acne induced erythema and scar

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181005041243N3

Enrollment

Registered

2022-10-15

Start date

2022-11-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne. Acne

Interventions

Intervention 1: Intervention group: Nd-YAG laser is treated on one side of the patient's face with setting and PD=25 ms and SS=4 mm. The treatment session would be 4 times every two weeks. Interventio

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Aged 18-60 Clinical diagnosis of moderate acne by a dermatologist

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding during the intervention history of internal diseases, including endocrine diseases causing acne Alteration in diet and lifestyle during the study Having consumed systemic therapy for acne in the last 4 weeks Having consumed oral antibiotics in the last 3 months Having consumed topical therapy for acne in the last 2 weeks Having consumed isotretinoin, undertaken laser, and peeling in the last 6 months Photosensitivity Severe or nodularis acne Polycystic ovary syndrome

Design outcomes

Primary

Measure	Time frame
Acne severity. Timepoint: At the first session and then 2 and 5 months after that. Method of measurement: Acne severity will be assessed based on Hayashi acne grading/ based on the observations of two dermatologists assessing the before and after photographs.;Acne scarring. Timepoint: At the first session and then 2 and 5 months after that based on the size of the scarring in millimeters. Method of measurement: Acne scarring will be assessed based on The Goodman quantitative postacne scarring grading system / based on the observations of two dermatologists assessing the before and after photographs.;Pain scoring during laser. Timepoint: At each treatment session (4 times). Method of measurement: Visual analogue scale.	—

Measure

Time frame

Acne severity. Timepoint: At the first session and then 2 and 5 months after that. Method of measurement: Acne severity will be assessed based on Hayashi acne grading/ based on the observations of two dermatologists assessing the before and after photographs.;Acne scarring. Timepoint: At the first session and then 2 and 5 months after that based on the size of the scarring in millimeters. Method of measurement: Acne scarring will be assessed based on The Goodman quantitative postacne scarring grading system / based on the observations of two dermatologists assessing the before and after photographs.;Pain scoring during laser. Timepoint: At each treatment session (4 times). Method of measurement: Visual analogue scale.

—

Secondary

Measure	Time frame
The side effects of laser therapy, including erythema, edema, and blisters. Timepoint: It would be evaluated after each treatment session. Method of measurement: Dermatologist's visit and patients statements.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNika Kianfar

Tehran University of Medical Sciences

n-kianfar@alumnus.tums.ac.ir+98 21 5563 0553

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026