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Effect of spironolactone and erythromycin solution in treatment of acne

Efficacy and safety of spironolactone 2% versus erythromycin 4% in treating patients with acne

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181005041243N1
Enrollment
90
Registered
2022-09-16
Start date
2022-11-10
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne. Acne

Interventions

Intervention 1: Intervention group 1: spironolactone 2% solution. Intervention 2: Intervention group 2: erythromycin 4% solution. Intervention 3: Intervention group 3: spironolactone 2% solution ???

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Aged 18-40 Acne diagnosis by a dermatologist

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding during the intervention history of internal diseases, including endocrine diseases causing acne alteration in diet and lifestyle during the study having consumed systemic therapy for acne in the last 4 weeks having consumed oral antibiotics in the last 3 months having consumed topical therapy for acne in the last 2 weeks having consumed isotretinoin, undertaken laser, and peeling in the last 6 months Photosensitivity severe or nodularis acne polycystic ovary syndrome

Design outcomes

Primary

MeasureTime frame
??Acne severity index. Timepoint: At the beginning of the study (before the start of the intervention) and 6 and 12 weeks after the start of trial. Method of measurement: Acne severity index (ASI) formula.;Patients' satisfaction with acne recovery. Timepoint: At the beginning of the study (before the start of the intervention) and 6 and 12 weeks after the start of trial. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNika Kianfar

Tehran University of Medical Sciences

nika_kianfar@yahoo.com+98 21 5563 0553

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026