Breast cancer & Radiotherapy. Malignant neoplasm of breast
Conditions
Interventions
Intervention 1: The intervention group: Women with breast cancer will receive radiotherapy with the standard technique of two-sided 5000CG / 25F photon tangent in the radiation center at Imam Khomein
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Have the ability to read and write in farsi or be able to communicate if they are illiterate. Women aged 18 and over Women with breast cancer who receive radiation dosage during treatment with the standard technique of bilateral tangent 5000CG / 25F Photon. Awareness of the person, time and place The possibility of making direct telephone calls to a patient or an active member of his family (to follow the samples) Based on bra / breast size =85 Women without known diseases and under medical treatmentSuch as diabetes, thyroid disorders, known liver disease, immune system weakness, rhabdomyolysis and cardiovascular disease, hyperlipidemia, depression and anxiety and taking statins with a doctor's order. Not using a psychologist or psychiatrist's counsel at the time of the study or at least a month before the study begins.
Exclusion criteria
Exclusion criteria: Allergy to atorvastatin Taking anti-inflammatory drugs Addicted to alcohol, cigarettes and drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of skin inflammation. Timepoint: Patients will be examined for the first time before the intervention and then the end of each week until two weeks after the completion of radiotherapy, this examination will be done. Method of measurement: radiation therapy oncology group (RTOG).;Evaluation of the degree of itching,. Timepoint: Patients will be examined for the first time before the intervention and then the end of each week until two weeks after the completion of radiotherapy, this examination will be done. Method of measurement: visual scale analog.;Assessing the amount of pain. Timepoint: Patients will be examined for the first time before the intervention and then the end of each week until two weeks after the completion of radiotherapy, this examination will be done. Method of measurement: visual scale analog.;Evaluation of C reactive proteains. Timepoint: The CRP marker is measured once before the intervention and once after the completion of radiotherapy. Method of measurement: This marker is quantitatively quantified by assessing the blood serum of patients.;Evaluation of oxidative stress in blood. Timepoint: Once in the first intervention and once after the completion of radiotherapy, the patient's serum is measured. Method of measurement: This marker is quantitatively quantified by assessing the blood serum of patients.;Evaluation of burning rate. Timepoint: Patients will be examined for the first time before the intervention and then the end of each week until two weeks after the completion of radiotherapy, this examination will be done. Method of measurement: visual scale analog.;Evaluate the amount of edema. Timepoint: Patients will be examined for the first time before the intervention and then the end of each week until two weeks after the completion of radiotherapy, this examination will be done. Method of measurement: Self-declaration of patients and clinical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Before intervention radiotherapy and after the completion of radiotherapy. Method of measurement: 1. A questionnaire for quality of life for cancer patients EORTC QLQ – BR23 . 2. The quality of life of cancer patients belonging to the European Cancer Research Organization and the specific breast cancer questionnaire EORTC QLQ C-30. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Jalal Hosseinimehr
Sari University of Medical Sciences
Outcome results
None listed