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Effect of ursobil on neonatal bilirubin

Effect of ursodeoxycholic acid on neonatal unconjugated bilirubin

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20181003041225N1
Enrollment
60
Registered
2019-03-07
Start date
2019-03-11
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal hyperbilirubinemia. neonatal jundice, unspecified

Interventions

Intervention 1: Intervention group: one 300mg ursodeoxycholic acid capsule (Abidi company) is dissolved in 10 cc sterile water.Then 1 cc of this solution is diluted with 5 cc sterile water and is giv

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Days to 7 Days

Inclusion criteria

Inclusion criteria: Body weight 2500-4000 gram Exclusive breast feeding Gestational age 38-41 weeks Total bilirubin 14-20 Direct bilirubin less than 2

Exclusion criteria

Exclusion criteria: ABO or Rh incompatibility Neonatal G6PD deficiency Sepsis symptoms Thyroid dysfunction Liver diseases Prematurity Maternal diabetes

Design outcomes

Primary

MeasureTime frame
Percentage of the patients receiving unconjugated bilirubin 12, within 24 hours of admission. Timepoint: Unconjugated bilirubin level at the beginning of the study and every 12 hours to reach bilirubin 12. Method of measurement: Serum bilirubin.

Secondary

MeasureTime frame
Duration of hospitalization. Timepoint: Time interval of admission to discharge. Method of measurement: Checking hours of hospitalization.;Different side effects like diarrhea, vomiting, skin rash. Timepoint: Time interval of admission to 1 week after discharge. Method of measurement: History and physical exam.;Determining the percentage of patients receiving bilirubin 12, after 24 hours and before 48 hours of admission. Timepoint: 24 and 48 hours after being admitted. Method of measurement: Serum bilirubin.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForouzan Rahimpour

Ahvaz University of Medical Sciences

rahimpur.f@ajums.ac.ir+98 61 3333 0074

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026