The assessment of Curcumin in compare with olfactory training and placebo on the smell activity in chronic kidney disease and diabetes mellitus patients

The assessment of Curcumin in compare with olfactory training and placebo on the smell activity in chronic kidney disease and diabetes mellitus patients in Shiraz University of Medical Sciences in 1401-1400

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20181001041190N2

Enrollment

Registered

2021-08-16

Start date

2021-08-23

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Chronic kidney disease. Condition 2: Disturbances of smell. Chronic kidney disease (CKD) Disturbances of smell and taste

Interventions

Intervention 1: Intervention group: Daily consumption of one capsule of 500 mg of turmeric extract (containing 475 mg of curcuminoid, Karen Company) for 8 weeks. Intervention 2: Control group: Daily c

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 50>Age>18 Willingness to participate in the study and sign informed consent Definitive diagnosis of chronic kidney disease by nephrologist At least 6 months after the diagnosis of the disease Glomerular filtration rate less than 60

Exclusion criteria

Exclusion criteria: Use aspirin and warfarin Lactation pregnancy Mental illness Having gallstones Usage of other complementary medicine methods Usage of other antioxidant treatment other than Nephrovit pills

Design outcomes

Primary

Measure	Time frame
Olfactory threshold. Timepoint: Before intervention and 8 weeks after intervention in drug and placebo groups-Before intervention and 2 weeks after intervention in olfactory training group. Method of measurement: Minimum olfactory level based on standard kits questioner of Iran-SIT (Iran Smell Identification Test).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Malekmakan

Shiraz University of Medical Sciences

malekmakan_l@yahoo.com+98 71 3235 7282

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026