coronary heart disease. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Intervention group: hyporthermic group: In this group, the temperature of the body was reduced untile 30- 34.9 ° C by a heater-cooler and a blanket (temperature changer). Intervention
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 85 Years
Inclusion criteria
Inclusion criteria: All adult patients undergoing heart surgery Patients between 25 and 85 years
Exclusion criteria
Exclusion criteria: History of thrombosis bleeding regular aspirin use in the past 5 days congenital fibrinogen disorders liver disease disorders or coagulation deficiencies genetic disorders such as hemophilia chronic renal failure patients people with substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of fibrinogen consumed and the production of fibrinogen degradation products. Timepoint: At the beginning of the study (before the intervention) and during the bypass in two intervals after the intervention. Method of measurement: Fibrinogen using the clauss and FDP method with serology (kit ELISA). | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative bleeding. Timepoint: 24 hours after entering ICU. Method of measurement: Measuring Chest tube bleeding. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahram Ghasemzadeh
Shiraz University of Medical Sciences
Outcome results
None listed