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The effects of family-centered affective stimulation on narcotic poisoning comatose patients’ level of consciousness and cortex activity

Comparison of the effects of family-centered affective stimulation and sensory stimulation on narcotic poisoning comatose patients’ level of consciousness and cortex activity

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180930041185N2
Enrollment
90
Registered
2019-10-01
Start date
2019-10-23
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coma caused by opium poisoning. injury, poisoning and certain other consequences of external causes

Interventions

Intervention 1: Intervention group 1: Intervention 1 in the experimental group: family-centered affective stimulation In the experimental group, a close family member (father, mother, spouse, child, s

Sponsors

National Institute of Medical Research Development (NIMAD)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Affliction by opium poisoning A Glasgow Coma Scale (GCS) score of 5–8 Age of 18–65 year

Exclusion criteria

Exclusion criteria: Patients who discharged from the ICU Death for any reason Needed an emergency therapeutic intervention Other poisoning in addition to narcotic drugs Stroke or other cerebral events History of CVA and drug abuse Use of psychiatric drugs during the study

Design outcomes

Primary

MeasureTime frame
The score of consciousness level is measured by the GCS scale and patients are selected with a score of 5 to 8. Post-intervention level of consciousness score can range from 3 to 15 which is measured and recorded by the research fellow nurses. Timepoint: Twice a day (morning and evening) up to 7 days. Method of measurement: Before and after intervention by a fellow nurse.;Cortical activity recorded by EEG is interpreted and analyzed by a neurologist.EEG signals will be recorded with a digital 26-channel scalp EEG device (g.tec, Guger Technologies, Graz, Austria), using the international 10-20 system. The EEG data will be acquired with a linked ear reference, sampled at 256 Hz with filter between 0.1Hz and 40Hz. Timepoint: Once a day every 7 days. Method of measurement: Every day before and after the intervention (morning shift) every 7 days.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEesa Mohammadi

Faculty of Medical Sciences of Tarbiat Modares University

mohamade@moderes.ac.ir+98 21 8288 3550

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026