Effect of low level laser on nerve healing

Effect of low – level laser irradiation on healing process of lower lip hypoesthesia following sagittal split ramus osteotomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180930041179N1

Enrollment

Registered

2018-12-21

Start date

2017-10-12

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurosensory disturbance in facial area. Other disorders of trigeminal nerve

Interventions

Intervention 1: Intervention group: Laser irradiation would be performed immediately, 24 hours, 48 hours, and 72 hours following surgery. Laser therapy is continued three times a week in the next two

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo sagittal split osteotomy surgery. Nerve damage is as neuropraxia. No technical error is occurred during surgery. No previous facial surgery is mentioned. No previous nerve damage is mentioned. Patients are not medically compromised. Patients do not consume anticonvulsants and antidepressants drugs.

Exclusion criteria

Exclusion criteria: History of previous orthognathic surgery History of neurosensory disturbance in the facial area Inappropriate surgical technique or complication occurrence Neurotmesis or axonotmesis happening Medically compromised patients Uncooperative patients

Design outcomes

Primary

Measure	Time frame
Patient’s satisfaction. Timepoint: One, three, six, and twelve months after laser therapy. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Pinprick test. Timepoint: One, three, six, and twelve months after laser therapy. Method of measurement: Pinprick test; is defined as the patient’s ability to identify the sharp needle touching the affected skin. Dental probe is used for this test with the constant force.;Thermal test. Timepoint: One, three, six, and twelve months after laser therapy. Method of measurement: Thermal test; which is defined as the patient’s ability to discern either the heat or cool probe. Small glass tubes containing water at15°C and 50°C are used. The perception of either cold or hot stimulus is recorded.;Two-point discrimination. Timepoint: One, three, six, and twelve months after laser therapy. Method of measurement: Two-point discrimination test; which is defined as the patient’s ability to detect the two nearby objects contacting the face skin truly two distinct points, not one. A calibrated drawing compass was used with minimum error (reproducibility more than 95%).	—

Measure

Time frame

Pinprick test. Timepoint: One, three, six, and twelve months after laser therapy. Method of measurement: Pinprick test; is defined as the patient’s ability to identify the sharp needle touching the affected skin. Dental probe is used for this test with the constant force.;Thermal test. Timepoint: One, three, six, and twelve months after laser therapy. Method of measurement: Thermal test; which is defined as the patient’s ability to discern either the heat or cool probe. Small glass tubes containing water at15°C and 50°C are used. The perception of either cold or hot stimulus is recorded.;Two-point discrimination. Timepoint: One, three, six, and twelve months after laser therapy. Method of measurement: Two-point discrimination test; which is defined as the patient’s ability to detect the two nearby objects contacting the face skin truly two distinct points, not one. A calibrated drawing compass was used with minimum error (reproducibility more than 95%).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Esmaeelinejad

Semnan University of Medical Sciences

esmaeelnejad@gmail.com+98 23 3332 4700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026