Comparison of efficacy of low vs. high dose of Atorvastatin and Rosuvastatin in reducing hs-CRP and IL-6 in diabetic patient referred to the Institute of Endocrinology and Metabolism

Comparison of efficacy of low dose of Atorvastatin and Rosuvastatin versus high dose of Atorvastatin and Rosuvastatin in reducing hs-CRP and IL-6 in diabetic patient referred to the Institute of Endocrinology and Metabolism

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180929041169N2

Enrollment

100

Registered

2019-01-10

Start date

2018-09-23

Completion date

Unknown

Last updated

2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Efficacy of low dose and high dose Atorvastatin and Rusovastatin in Diabetic patients.

Interventions

Intervention 1: Diabetic patients between 40 to 75 years old(no use of lower lipid drugs in past 2 month) are divided to four groups. Each group contains 25 patients. 1st group of intervention will re

Eligibility

Sex/Gender

All

Age

40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Diabetic patients who need to receive Statin according to ADA 2018

Exclusion criteria

Exclusion criteria: Pregnancy Patient with Genetic Disease Use of other lowering agent other than Statin Hx of Angina Hx of Nephropathy Hx of Hypothyroidism Hx of liver Disease or ALT> 3 ULN,AST>3 ULN CPK> 10 ULN Patients on Corticosteroids Patients with Cyclosporins or Hormone replacement therapy Hx of use of Alcohol Acute and chronic infectious or Inflammatory disease

Design outcomes

Primary

Measure	Time frame
Measurement of highly sensitive C reactive protein & Interleukin-6. Timepoint: At the initial and 2 month after medication used. Method of measurement: Blood sampling with Elisa assay.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Taghi Gorji

Iran University of Medical Sciences

dr.hgorji@yahoo.com+98 21 8603 6064

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026