Comparison effect of Lavender and Acetaminophen on Nitroglycerin-induced headache

Comparison the effect of aromatherapy with Lavender essential oil versus Acetaminophen tablet on Nitroglycerin-induced headache and comfort in the patients with angina pectoris in Cardiac Care Units

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180927041157N1

Enrollment

Registered

2018-11-10

Start date

2018-10-23

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina. Ischaemic heart diseases

Interventions

Intervention 1: Intervention Group: The Acetaminophen Group: Oral Acetaminophen (500 mg) of the Alborz Drug Company is prescribed by the physician as needed(PRN), which is given to a patient 15 minute

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Receiving Nitroglycerin infusion for the first time Receiving Acetaminophen PRN Not having a history of sublingual Nitroglycerin use Not having a history of migraine or chronic headaches No sensitivity to Acetaminophen No sensitivity to medicinal Plants Lack of olfactory disorders Ability to swallow Ability to speak

Exclusion criteria

Exclusion criteria: Hypotension Drug susceptibility

Design outcomes

Primary

Measure	Time frame
Pain scale by VAS scale. Timepoint: The evaluation of the patient's headache at 5, 10, 15, and 60 minutes after the onset of Nitroglycerine infusion. Method of measurement: The evaluation of the patient's headache in three groups (Acetaminophen, Lavender essential oil and control) at 5, 10, 15, and 60 minutes after the onset of Nitroglycerine infusion will be measured.;Comfort scale by VAS scale. Timepoint: The evaluation of the patient's comfort 15 minutes before infusion and at 60 minutes after initiation of nitroglycerin infusion. Method of measurement: The evaluation of the patient's comfort (VAS) 15 minutes before infusion and at 60 minutes after initiation of nitroglycerin infusion in three groups (acetaminophen, lavender essential oil and control) will be measured.	—

Measure

Time frame

Pain scale by VAS scale. Timepoint: The evaluation of the patient's headache at 5, 10, 15, and 60 minutes after the onset of Nitroglycerine infusion. Method of measurement: The evaluation of the patient's headache in three groups (Acetaminophen, Lavender essential oil and control) at 5, 10, 15, and 60 minutes after the onset of Nitroglycerine infusion will be measured.;Comfort scale by VAS scale. Timepoint: The evaluation of the patient's comfort 15 minutes before infusion and at 60 minutes after initiation of nitroglycerin infusion. Method of measurement: The evaluation of the patient's comfort (VAS) 15 minutes before infusion and at 60 minutes after initiation of nitroglycerin infusion in three groups (acetaminophen, lavender essential oil and control) will be measured.

—

Countries

Iran (Islamic Republic of)

Contacts

Public Contact?Arezo Karamporian

Hamedan University of Medical Sciences

a.karampourian@umsha.ac.ir+98 81 3262 1123

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026