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Effect of Melissa Officinalis syrup on Melasma

Explanation of "KALAF" in Persian Medicine, and Assessment of the effects of Melissa Officinalis syrup on Melasma: A Randomized, triple-Blind, controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180927041149N1
Enrollment
106
Registered
2020-01-05
Start date
2019-01-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasma - Stress Disorders - Sleep Disorders. Chloasma

Interventions

Intervention 1: Intervention group: Melissa Officinalis syrup 10 gr twice a day, inclusive aqueous extract of 3 gr Melissa Officinalis, aqueous extract of 1 gr Fennel fruit, 8 gr Rosa Damascena, suga

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Melasma diagnosis by Dermatologist (at the Center for Research and Training in skin disease And Leprosy) Age> 18 years

Exclusion criteria

Exclusion criteria: Using local treatment for melasma during 2 weals before play at research Using systemic treatment for any systemic disease Diabetes, thyroid disorder, Hypermenorrhea Oral Contraceptive Drugs and hormonal drugs during 4 weals before play at research Pregnancy, Lactation

Design outcomes

Primary

MeasureTime frame
Darkness and width of Melasma patch. Timepoint: At the start of study and 3 month later. Method of measurement: Mexameter - Vissioface.

Secondary

MeasureTime frame
Anxiety, Sleep disorder. Timepoint: The first of study and 3 months later. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLida

Tehran University of Medical Sciences

lidabakhtyari@yahoo.com+98 25 3770 3934

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026