Traumatic Cervical Spinal Cord Injury. Injury of nerves and spinal cord at neck level
Conditions
Interventions
Intervention 1: Control group: methyl prednisolone (500 mg lyophilized vials, Ronak Daroo, Iran), 30 mg/kg IV infusion for the first hour followed by 5.4 mg/kg/h in the next 23 hours if referred withi
or if referred to the ED between the third and eighth hour after the trauma underwent treatment based on National Acute Spinal Cord Injury Study (NASCIS) III protocol for the following 47 hours. Inter
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patient with Acute Traumatic Cervical Spinal Cord Injury Admitted within 8 hours of injury Neurological lesion at C5 to C7 level Stable hemodynamics
Exclusion criteria
Exclusion criteria: Vascular Brain Disease Acute Myocardial Infarction Thrombotic Diseases Cardiac Arrhythmia Heart Failure Peripheral Vascular Disorders Polycythemia Porphyria Malignancy Neurological Disorders Known Psychiatric Disorders Acute or Chronic Kidney Disease Acute Spinal Cord Injury caused by weapons Pregnancy Lactation Allergy to Erythropoietin or Human Albumin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| American Spinal Injury Association (ASIA) score. Timepoint: Baseline, 6 and 12 months after intervention. Method of measurement: Medical History and Physical Examination.;Sphincter Function. Timepoint: Baseline, 6 and 12 months after intervention. Method of measurement: Physical Examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGholamreza Bahadoorkhan
Mashhad University of Medical Sciences
Outcome results
None listed