Vaginal atrophy. Postmenopausal atrophic vaginitis
Conditions
Interventions
Intervention 1: Intervention group: Alcea vaginal suppository(5%) every night for 2 weeks, followed by every other night administration for a further 6 weeks. Duration of treatment is 8 weeks. All sta
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: Married women, and have sexual activity; Age between 40-65 years; Complaint of vaginal dryness; Amenorrhea for at least 12 months, or laboratory confirmation of menopause(FSH>40); Amenorrhea after surgery and Bilateral Oophorectomy;
Exclusion criteria
Exclusion criteria: Endometrial cancer or breast cancer or suspicion of it; Vaginal bleeding with unknown causes; Vaginal infection; History of sensitivity to the Alcea; Chronic diseases; The history of consumption of hormonal products containing estrogen and progesterone in the last month; The history of vaginal use of stimulants that can cause chronic vaginal itching (scents, moisturizers, soaps) in the last month;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Sexual satisfaction. Timepoint: Before intervention, Eight weeks after intervention. Method of measurement: Standard Questionnaire for Assessment of Female Sexual function (FSFI). | — |
Primary
| Measure | Time frame |
|---|---|
| Symptoms of vaginal atrophy. Timepoint: Before intervention, Eight weeks after intervention. Method of measurement: The most bothersome symptom of vaginal mucosa with Visual Analogue Scale.;Vaginal superficial cells. Timepoint: Before intervention, Eight weeks after intervention. Method of measurement: vaginal maturation index.;Vaginal PH. Timepoint: Before intervention, Eight weeks after intervention. Method of measurement: PH meter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlieh Kiani Talaei
Gorgan University of Medical Sciences
Outcome results
None listed