The effect of aerobic exercise and garlic supplementation on interleukin 6 (IL6), erythrocyte sedimentation rate (ESR) and fatigue in women with rheumatoid arthritis

Acute and chronic effects of a course of aerobic exercise training and garlic supplementation on serum levels of interleukin 6 (IL6), erythrocyte sedimentation rate (ESR) and fatigue in women with Rheumatoid Arthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180923041097N4

Enrollment

Registered

2021-11-27

Start date

2021-09-11

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis. Felty's syndrome, unspecified hand

Interventions

Intervention 1: Intervention group 1: A group that performs 8 weeks of aerobic exercise, 3 sessions per week and 1 hour per session with an intensity of 70% of the maximum heart rate on the ergometer

Eligibility

Sex/Gender

Female

Age

27 Years to 45 Years

Inclusion criteria

Inclusion criteria: Rheumatoid arthritis patients Women who are menstruating The age range of 25 - 45 years

Exclusion criteria

Exclusion criteria: Cardiovascular disease Menopausal women

Design outcomes

Primary

Measure	Time frame
Inflammatory factor interleukin-6, the amount of which is above 20 pg/ml by ELISA kit. Timepoint: 24 hours before the first session of the exercise training program and 24 hours after the last session of the exercise training program. Method of measurement: Interleukin-6 ELISA kit.;Erythrocyte Sedimentation Rate above 35 mm/hr. Timepoint: 24 hours before and 24 hours after the first session and the last session of the exercise training program. Method of measurement: Westergren method.;Fatigue rate, which was considered above 3 on average. Timepoint: 24 hours before and 24 hours after the first session and the last session of the exercise training program. Method of measurement: Fatigue Severity Inventory (FSI) Questionnaire.	—

Measure

Time frame

Inflammatory factor interleukin-6, the amount of which is above 20 pg/ml by ELISA kit. Timepoint: 24 hours before the first session of the exercise training program and 24 hours after the last session of the exercise training program. Method of measurement: Interleukin-6 ELISA kit.;Erythrocyte Sedimentation Rate above 35 mm/hr. Timepoint: 24 hours before and 24 hours after the first session and the last session of the exercise training program. Method of measurement: Westergren method.;Fatigue rate, which was considered above 3 on average. Timepoint: 24 hours before and 24 hours after the first session and the last session of the exercise training program. Method of measurement: Fatigue Severity Inventory (FSI) Questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza ?Delavar

University of Sistan and Baluchestan

delavar@ped.usb.ac.ir+98 54 3113 6724

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026