Type 2 diabetes. Type 2 diabetes mellitus with kidney complications
Conditions
Interventions
Intervention 1: Control group: The subjects in this group did not do any exercise during the research period (6 weeks) and did not receive any supplements. Intervention 2: The second intervention grou
Sponsors
University of Sistan and Baluchestan
Eligibility
Sex/Gender
Male
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: Criteria for inclusion in the study: - male gender. - Having type 2 diabetes as diagnosed by a doctor. - Age 40 to 60 years old. - Physical strength required to attend a exercise protocol for 2 months.
Exclusion criteria
Exclusion criteria: Criteria for non-inclusion in the study were: - cardiovascular disease. - Asthma. - having a history of broken limbs. - The use of insulin. - complications of diabetes, including diabetic foot ulcers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood creatinine, The normal level of creatinine is 0.8 to 1.4 mg/dL. Females usually have a lower creatinine (0.6 to 1.2 mg/dL) than males, because they usually have less muscle mass. Creatinine is a by-product of normal muscle breakdown. Measuring the levels of creatinine in the bloodstream and in the urine can be helpful for tracking the progression of diabetic kidney disease. Timepoint: Primary blood sampling was performed 24 hours before the start of exercise training protocol and final stage blood sampling was performed 48 hours after the last exercise training session. Method of measurement: To measure serum creatinine, a technical creatinine assay kit made by Pars Azmoun Company, Iran, was used.;Diabetes is associated with quantitative changes in the amount of circulating lipids – notably an reduction in HDL. Like other lipoproteins, HDL also undergoes significant qualitative changes in diabetes, in both structure and function. Timepoint: Measurement of serum lipoprotein HDL was performed in two stages, the first stage in the initial blood sampling, ie 24 hours before the start of exercise training protocol and the second stage in the final stage blood sampling, ie 48 hours after the last exercise session. Method of measurement: To measure the concentration of HDL index (mg / dL), deposition method with bridging anions and divalent cations was used.;LDL cholesterol levels in people with diabetes are not higher than those in people without diabetes who are matched for age, sex, and body weight. In fact, the most common LDL cholesterol level in diabetes is “borderline high” (130-159 mg/dl). Timepoint: Measurement of serum lipoprotein LDL was performed in two stages, the first stage in the initial blood sampling, ie 24 hours before the start of exercise training protocol and the second stage in the final stage blood sampling, ie 48 hours after the last exercise session. Method of measurement: The Friedwall equation was used to measure the concentration of LDL ( | — |
Secondary
| Measure | Time frame |
|---|---|
| Determines of kidney disease level based on the presence of kidney damage and glomerular filtration rate (GFR), which is a measure of level of kidney function, as chronic kidney disease progresses, GFR number decreases. Timepoint: The calculation of glomerular filtration of the subjects was done in two stages, the first stage in the initial blood sampling, ie 24 hours before the start of exercise training protocol and the second stage in the final stage blood sampling, ie 48 hours after the last exercise session. Method of measurement: Glomerular filtration rate (GFR) was also calculated from the following formula. eGFR = [186 × (serum creatinine / 88.4) - 1.154] × (age) - 0.203 × (0.742). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Delavar
Sistan and Baluchestan University
Outcome results
None listed