Nephrolithiasis. Calculus of kidney
Conditions
Interventions
Intervention 1: Intervention group: IA specific amount of black pepper, black seed, black cumin, and ginger rhizome powder is ground and mixed with honey. The patient consumes 5 grams of this mixture
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Kidney stones 5 mm or larger in the lower pole of the kidney Age between 18 and 60 years old
Exclusion criteria
Exclusion criteria: severe urinary tract infection acute renal injury CKD diabetes concomitant use of herbal remedies to dissolve kidney stones such as Sankol®, Rowatinex®, Cystone®, Lithorex-B® or Urtica ZardBand® pregnant or lactating women patients with coagulation problems or taking anticoagulant medications a history of ulcers or erosions in the gastrointestinal tract
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal stone size. Timepoint: At the baseline (before the intervention) and 10 days after starting the drug. Method of measurement: Ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| BUN. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: blood test.;Serum creatinine. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: blood test.;Serum calcium. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: blood test.;Liver enzymes. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: blood test.;Urine specific gravity. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: Urine analysis.;24 h urine volume. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: Graduated container.;24 h urine calcium. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: Urine analysis.;24 h urine magnesium. Timepoint: At baseline (before the intervention) and 10 days after starting the drug. Method of measurement: Urine analysis.;Number of analgesics used. Timepoint: On days 1, 2, 3, 4, and 5 after the start of the intervention. Method of measurement: Asking the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHabib Ghaznavi
Zahedan University of Medical Sciences
Outcome results
None listed