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Evaluation of the effect of oral Ivermectin on patients with COVID-19

Evaluation of the effect of oral Ivermectin on the outcome of patients with COVID-19 and compare it with the effect of conucntional therapics in patients admitted to Ziaeian, Baharloo, Imam Khomeini in the spring and summer 2020

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180922041089N4
Enrollment
130
Registered
2020-08-23
Start date
2020-04-19
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corona virus. COVID-19, virus identified

Interventions

Intervention 1: Control group: Patients in the control group are treated with Hydroxychloroquine sulfate and Azithromycin (if there is no cardiac contraindication) according to the protocol of the Min

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients 18 to 50 years Infected by the COVID 19 virus Patients with clinical symptoms, history of exposure to the patient and a positive RT-PCR test for Covid 19 from A laboratory or characteristic signs on a CT scan of the chest) with mild to moderate clinical manifestations according to the National Early Warning Score (NEWS) (mild: 1-4 / moderate: 5-6) Obtaining informed written consent consciously

Exclusion criteria

Exclusion criteria: Severely ill and hospitalized in the intensive care unit Patients who are unable to take oral medications Patients with AST / ALT levels more than 5 times above normal Pregnant patients

Design outcomes

Primary

MeasureTime frame
Improving clinical symptoms. Timepoint: Daily. Method of measurement: National Early Warning Score? (NEWS).;Reducing the length of hospitalization. Timepoint: Daily. Method of measurement: Counting.;Improving paraclinical indicators of the disease. Timepoint: Daily lymphocyte count - the last day of hospital CT scan. Method of measurement: Lymphocyte count - CT scan.

Secondary

MeasureTime frame
Lack of response to treatment and hospitalization in the ICU. Timepoint: Daily. Method of measurement: Assessing clinical manifestations.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Zendehdel

Tehran University of Medical Sciences

azendedel@sina.tums.ac.ir+98 21 5517 6031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026